Code

Statistical Methods in Computational Biology | Spring 2024

• Single-cell RNA-seq Cell Type Annotation

• scRNA-seq Data Normalization Methods Comparison[real data][simulated data] and Simulation and Statistical Derivation of Negative Binomial scRNA-seq Model

• Dimension Reduction Methods: PCA, GLM-PCA, MDS, NMF, ICA, PNMF, t-SNE, and UMAP

• Clustering Algorithms: k-means, k-means++, hierarchical clustering, Seurat clustering, and Evaluation: ARI, Silhouette Score

Generalized Linear Models [course link] | Spring 2024

• Comparison of Four GLM Models for Microbiome Sequencing Data

  • In this project, I compared the performance of four GLM models (Quasi-Poisson, Negative Binomial, Zero-Inflated Poisson, and Zero-Inflated Negative Binomial) for differential abundance analysis of microbiome sequencing data at genus and species levels, assessing type I error rates with simulated data.

• Statistical Derivations in GLM

• Linear Models, GLM, Survival Analysis, and Longitudinal Data Analysis

Data Science [course link] | Winter 2024

• Linux Shell Commands, and HPC
• Ingesting Big Data Files, and Inquiry and Analysis on Database
• Big Data Visualization, and developing Shiny App for interactive graphics
• Statistical Learning in R

Statistical Simulation | Fall 2024

• Accept-Reject Algorithm
• Bayesian Estimation with Metropolis Hastings
• Poisson Process Simulation

Linear Models | Winter 2024

• [ Poster ] Assessing Key Factors Associated with Depression before Adjuvant Therapy in Women with Breast Cancer

Data Management | Fall 2023

• [ Report ] Modeling Depression Risk among Noninstitutionalized US Citizens: A Retrospective Study by SAS